We are receiving more and more calls related to Stevens Johnson Syndrome. The calls are heartbreaking. Of note is the number of the calls related to over the counter pain relievers such as Motrin and Children’s Motrin. Stevens Johnson Syndrome is treated with burn therapies. In Colorado we are fortunate to have excellent burn care units, but the recovery is extremely difficult. Despite excellent care, the symptoms can re-occur. There can also be permanent complications from TEN/SJS can include blindness, dry-eye syndrome, photophobia, lung damage, chronic obstructive pulmonary disease (COPD), asthma, permanent loss of nail beds, scarring of the esophagus and other mucous membranes, arthritis, and chronic fatigue syndrome. Many patients pores scar shut, causing their bodies to loose the ability to regulate temperature. A list of drugs linked to Steven Johnson Syndrome follows: Advil / ibuprofen Ansaid / flurbiprofen Bextra / valdexocib Cataflam / diclofenac Celebrex / celoxicab Children's Advil / motrin Clinoril / sulindac Daypro / oxaprozin Dolobid / diflunisal Feldene / piroxicam Indocin / indomethacin Lamictal / lamotrigine Lodine / etodolac Nalfon / fenoprofen Mobic / meloxicam Motrin / ibuprofen Naprosyn / naproxen Oruvail / ketoprofen Ponstel / mefenamic Relafen / nabumetone Tolectin / tolmetin Septra DS / (all sulpha antibiotics) Toradol / ketorolac Vioxx / rofecoxib Zithromax / azithromycin These drugs had recent modifications to the BOXED WARNING, CONTRAINDICATIONS and/or WARNINGS sections: Anaprox /Anaprox DS (naproxen sodium tablets) Ansaid (flurbiprofen tablets, USP) Arthrotec (diclofenac sodium/misoprostol) Tablets Cataflam (diclofenac potassium immediate-release tablets) Clinoril (sulindac) Tablets Daypro (oxaprozin) Caplets Daypro Alta (oxaprozin potassium) Tablets Depacon (valproate sodium injection) Depakene (valproic acid capsules and syrup) Depakote (divalproex sodium coated particles in capsules) Sprinkle Capsules Dolobid (diflunisal) Tablets Elidel (pimcerolimus) Cream 1% Feldene (piroxicam) Capsules Indocin (indomethacin) Capsules, Oral Suspension, and Suppositories Lodine (etodolac capsules and tablets) Lodine XL (etodolac extended-release tablets) Motrin (ibuprofen) Suspension 100 mg/5 mL Motrin (ibuprofen tablets, USP) Nalfon (fenoprofen calcium capsules, USP) Naprelan (naproxen sodium) Controlled-Release Tablets Naprosyn (naproxen tablets), Naprosyn (naproxen suspension), and EC-Naprosyn (naproxen delayed-release tablets Nimotop (nimodipine) Capsules For Oral Use Orudis (ketoprofen) Capsules and Oruvail (ketoprofen) Extended-Release Capsules) Ponstel (mefenamic acid capsules, USP) Protopic (tacrolimus) Ointment, 0.03% and 0.1% Relafen (nabumetone) Tablets Voltaren (diclofenac sodium enteric-coated tablets) Voltaren-XR (diclofenac sodium extended-release tablets) Parnate (tranylcypromine sulfate tablets) Aleve (220 mg naproxen sodium) Tablets Aleve Cold & Sinus (220 mg naproxen sodium and 120 mg pseudoephedrine HCl) Extended Release Tablets Aleve Sinus & Headache (220 mg naproxen sodium and 120 mg pseudoephedrine HCl) Extended Release Tablets Carbatrol (carbamazepine) Extended-Release Capsules Children's ElixSure IB (100 mg/5 mL ibuprofen) Suspension Junior Strength Advil (100 mg ibuprofen) Tablets Effexor (venlafaxine hydrochloride) Tablets Effexor XR (venlafaxine hydrochloride) Extended-Release Capsules Midol Extended Relief (220 mg naproxen sodium) Tablets Trilepal is another medication used to treat children with epilepsy. With every new case, we are finding that the number of drugs on our watch list are increasing. If you have been diagnosed with SJS, we want to know about your case and to do what we can to help.