Stevens Johnson Syndrome
We are receiving more and more calls related to Stevens Johnson Syndrome. The calls are heartbreaking. Of note is the number of the calls related to over the counter pain relievers such as Motrin and Children’s Motrin.
Stevens Johnson Syndrome is treated with burn therapies. In Colorado we are fortunate to have excellent burn care units, but the recovery is extremely difficult. Despite excellent care, the symptoms can re-occur. There can also be permanent complications from TEN/SJS can include blindness, dry-eye syndrome, photophobia, lung damage, chronic obstructive pulmonary disease (COPD), asthma, permanent loss of nail beds, scarring of the esophagus and other mucous membranes, arthritis, and chronic fatigue syndrome. Many patients pores scar shut, causing their bodies to loose the ability to regulate temperature.
A list of drugs linked to Steven Johnson Syndrome follows:
Advil / ibuprofen
Ansaid / flurbiprofen
Bextra / valdexocib
Cataflam / diclofenac
Celebrex / celoxicab
Children’s Advil / motrin
Clinoril / sulindac
Daypro / oxaprozin
Dolobid / diflunisal
Feldene / piroxicam
Indocin / indomethacin
Lamictal / lamotrigine
Lodine / etodolac
Nalfon / fenoprofen
Mobic / meloxicam
Motrin / ibuprofen
Naprosyn / naproxen
Oruvail / ketoprofen
Ponstel / mefenamic
Relafen / nabumetone
Tolectin / tolmetin
Septra DS / (all sulpha antibiotics)
Toradol / ketorolac
Vioxx / rofecoxib
Zithromax / azithromycin
These drugs had recent modifications to the BOXED WARNING, CONTRAINDICATIONS and/or WARNINGS sections:
Anaprox /Anaprox DS (naproxen sodium tablets)
Ansaid (flurbiprofen tablets, USP)
Arthrotec (diclofenac sodium/misoprostol) Tablets
Cataflam (diclofenac potassium immediate-release tablets)
Clinoril (sulindac) Tablets
Daypro (oxaprozin) Caplets
Daypro Alta (oxaprozin potassium) Tablets
Depacon (valproate sodium injection)
Depakene (valproic acid capsules and syrup)
Depakote (divalproex sodium coated particles in capsules) Sprinkle Capsules
Dolobid (diflunisal) Tablets
Elidel (pimcerolimus) Cream 1%
Feldene (piroxicam) Capsules
Indocin (indomethacin) Capsules, Oral Suspension, and Suppositories
Lodine (etodolac capsules and tablets)
Lodine XL (etodolac extended-release tablets)
Motrin (ibuprofen) Suspension 100 mg/5 mL
Motrin (ibuprofen tablets, USP)
Nalfon (fenoprofen calcium capsules, USP)
Naprelan (naproxen sodium) Controlled-Release Tablets
Naprosyn (naproxen tablets), Naprosyn (naproxen suspension), and EC-Naprosyn
(naproxen delayed-release tablets
Nimotop (nimodipine) Capsules For Oral Use
Orudis (ketoprofen) Capsules and Oruvail (ketoprofen) Extended-Release
Capsules)
Ponstel (mefenamic acid capsules, USP)
Protopic (tacrolimus) Ointment, 0.03% and 0.1%
Relafen (nabumetone) Tablets
Voltaren (diclofenac sodium enteric-coated tablets)
Voltaren-XR (diclofenac sodium extended-release tablets)
Parnate (tranylcypromine sulfate tablets)
Aleve (220 mg naproxen sodium) Tablets
Aleve Cold & Sinus (220 mg naproxen sodium and 120 mg pseudoephedrine HCl)
Extended Release Tablets
Aleve Sinus & Headache (220 mg naproxen sodium and 120 mg pseudoephedrine
HCl) Extended Release Tablets
Carbatrol (carbamazepine) Extended-Release Capsules
Children’s ElixSure IB (100 mg/5 mL ibuprofen) Suspension
Junior Strength Advil (100 mg ibuprofen) Tablets
Effexor (venlafaxine hydrochloride) Tablets
Effexor XR (venlafaxine hydrochloride) Extended-Release Capsules
Midol Extended Relief (220 mg naproxen sodium) Tablets
Trilepal is another medication used to treat children with epilepsy.
With every new case, we are finding that the number of drugs on our watch list are increasing.
If you have been diagnosed with SJS, we want to know about your case and to do what we can to help.
