Colorado Toxic Epidermal Necrolysis Lawyer
We are currently representing individuals who have suffered injuries from Toxic Epidermal Necrolysis from the use of drugs. The following drugs are on our case watch list:
| Childrens Motrin | Aldactone | Motrin | Athrotec |
| Tegreta | Avalox | Dilantin | Zortaren |
| Trileptol | Coreg | Bextra | Septra |
| Feldene | Bactrim | Ceclor | Levaquin |
| Clinoril | Lamictal | Zantac | Ibuprofen |
| Neurontin | Avalox | Tylenol | Voltaren |
| Z-pack (Zithromax) | Phenytek | Prilosec | Relafen |
Steven Johnson Syndrome Verses Toxic Epidermal Necrolysis
A classification was developed for epidemiological purposes to distinguish between SJS and TEN. This classification proposes that SJS is less than 10% of surface area of skin is involved; greater than 10%-29% is called SJS-TEN overlap; and 30% or greater skin surface involvement is considered TEN. Some epidemiology studies in the U.S. have reported an incidence of SJS to be 7.1 per 1 million persons, and as high as 49 persons per 1 million will develop erythema multiforme, which is a milder form of SJS.
Females appear to be twice as affected by SJS and TEN than males. Children taking NSAIDs (Motrin, Advil) and anticonvulsants have recently been reported to have an increased risk of SJS and TEN.
Drugs cause over 80% of all cases of SJS and TEN. 90-95% of TEN cases are caused only by medications. While there have been very rare reports of infections causing SJS and TEN, most of those case reports were published long before scalded skin syndrome and TEN were distinguished by biopsy, making these cases more likely to have been caused by a drug. The rarity of these reports cast doubt on the reliability of information taken regarding drug intake, and doesn't change the fact that almost all cases of TEN are always caused by a single drug.
NSAIDs have recently been recognized by the scientific community to be one of the leading causes of SJS and TEN. A recently published study reported significantly increased risk for ibuprofen in an epidemiologic study published in 2003. (Anti convulsants and antibiotics are the other leading causes of these diseases.
There is also some evidence to support that pre-existing infections coupled with the ingestion of one of these drugs mentioned above causes a synergistic effect that leads to SJS and TEN, including antibiotics and OTC medications like Children's Advil and Children's Motrin.
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